{"id":7496,"date":"2021-09-27T11:17:09","date_gmt":"2021-09-27T09:17:09","guid":{"rendered":"https:\/\/www.cannabis.es\/pw\/?p=7496"},"modified":"2021-09-27T11:17:10","modified_gmt":"2021-09-27T09:17:10","slug":"el-cbd-bloquea-el-covid-en-celulas-pulmonares","status":"publish","type":"post","link":"https:\/\/www.cannabis.es\/pw\/2021\/09\/27\/el-cbd-bloquea-el-covid-en-celulas-pulmonares\/","title":{"rendered":"El CBD bloquea el covid en c\u00e9lulas pulmonares"},"content":{"rendered":"\n

Arnau Alcaide

El CBD, y no otros cannabinoides, impide la reproducci\u00f3n del covid e inhibe los s\u00edntomas en c\u00e9lulas ya infectadas, adem\u00e1s de activar la respuesta autoinmune del organismo. Es el resultado del estudio en Estados Unidos en un cultivo in vitro de c\u00e9lulas de tejido pulmonar. Llevado a cabo por un equipo multidisciplinar de 8 departamentos de la universidad de Chicago en colaboraci\u00f3n con el Howard Taylor Ricketts Laboratory de Lemont, se public\u00f3 en marzo y ya ha sido recogido<\/a> por multitud de revistas cient\u00edficas<\/a>.

\u00abEl CBD y su metabolito, el 7-OH-CBD, pero no los cannabinoides congen\u00e9ricos, bloquean de forma potente la replicaci\u00f3n del SARS-CoV-2 en las c\u00e9lulas epiteliales pulmonares. El CBD act\u00faa despu\u00e9s de la infecci\u00f3n celular, inhibiendo la expresi\u00f3n de genes virales y revirtiendo muchos efectos del SARS-CoV-2 en la transcripci\u00f3n de genes del hu\u00e9sped. El CBD induce la expresi\u00f3n de interfer\u00f3n y regula positivamente su v\u00eda de se\u00f1alizaci\u00f3n antiviral\u00bb<\/em><\/span>.<\/em> La motivaci\u00f3n del estudio surgi\u00f3 cuando detectaron menor incidencia de covid entre las personas usuarias, algo que bien pod\u00eda ser una correlaci\u00f3n, pero que a falta del ensayo cl\u00ednico con personas est\u00e1n cerca de probar, de acuerdo al est\u00e1ndar requerido.<\/p>\n\n\n\n

El estudio destaca que han probado otros cannabinoides aislados y no funcionaba. Incluso en combinaci\u00f3n con THC, este inhib\u00eda el potencial del CBD en la respuesta celular si se inoculaba una misma cantidad de ambos. Con el uso de CBD obtenido de tres fuentes diferentes, tambi\u00e9n han probado el efecto antiviral en la variante beta del covid y en la hepatitis de ratones, con resultados satisfactorios, por lo que realzan el potencial del estudio del efecto antiviral del cannabidiol. Se trata, eso s\u00ed, de cannabidiol de alta pureza, bien purificado o natural, pues tambi\u00e9n contaban con un proveedor de CBD natural con un 97% de pureza y el resto de cannabinoides por debajo del 1%.

Los responsables del estudio piden cautela y advierten contra la toma de CBD obtenido por las v\u00edas com\u00fanmente disponibles con este fin. Eso s\u00ed, reclaman que la investigaci\u00f3n siga avanzando hacia al estadio del estudio cl\u00ednico con personas sin el paso por animales, ante un resultado m\u00e1s que prometedor, y proponen la f\u00f3rmula del estudio con grupo de control que toma placebo y el grupo que toma CBD, este de alta concentraci\u00f3n, que es el ensayo cl\u00ednico m\u00e1s habitual.<\/p>\n\n\n\n

\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"Tiempo de lectura:<\/span> 2<\/span> minutos<\/span><\/span>Arnau AlcaideEl CBD, y no otros cannabinoides, impide la reproducci\u00f3n del covid e inhibe los s\u00edntomas en c\u00e9lulas ya infectadas, adem\u00e1s de activar la respuesta autoinmune del organismo. Es el resultado del estudio en Estados Unidos en un cultivo in vitro de c\u00e9lulas de tejido pulmonar. Llevado a cabo por un equipo multidisciplinar de 8 […]","protected":false},"author":3,"featured_media":7514,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"loftocean-featured-post":"","loftocean_post_format_gallery":"","loftocean_post_format_gallery_ids":"","loftocean_post_format_gallery_urls":"","loftocean_post_format_video_id":"","loftocean_post_format_video_url":"","loftocean_post_format_video_type":"","loftocean_post_format_video":"","loftocean_post_format_audio_type":"","loftocean_post_format_audio_url":"","loftocean_post_format_audio_id":"","loftocean_post_format_audio":"","loftocean_post_format_quote_text":"","loftocean_post_format_quote_byline":"","loftocean_post_format_link_text":"","loftocean_post_format_link_url":"","ceramag_post_header_style":"","ceramag_enable_background_video":"","ceramag_show_in_top_slider":"","ceramag_post_background_video_start":"","ceramag_post_background_video_end":"","loftocean_page_background_video_id":"","loftocean_page_background_video_url":"","loftocean_page_background_video_type":"","loftocean_page_background_video":"","ceramag_background_video_start":"","ceramag_background_video_end":"","ceramag_single_page_hide_header":"","footnotes":""},"categories":[36],"tags":[540,52,551,53],"class_list":["post-7496","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal","tag-arnau-alcaide","tag-cannabis-medicinal","tag-cbd","tag-investigacion"],"yoast_head":"\nEl 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